Karl August Folkers
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Karl August Folkers
Karl August Folkers
Born
September 1, 1906
Died
December 7, 1997
(aged 91)
Known for
Awards
(1941)
(1960)
(1967)
(1972)
(1986)
(1990)
Scientific career
Fields
Institutions
Karl August Folkers
(September 1, 1906 – December 7, 1997) was an American
who made major contributions to the isolation and identification of
bioactive
.
Career
[
]
Folkers graduated from the College of Liberal Arts and Sciences at the
in 1928. In 1986, the institution awarded him its
Alumni Achievement Award.
His career was mainly spent at
. He played a prominent role in the
isolation of
in 1947, which is one of the most structural complex
of the vitamins.
As a Merck Pharmaceuticals research team, Folkers,
, and Edward Anthony Kaczka were the first to isolate the antibiotic
in 1955.
His team also isolated the antibiotic
.
In 1958 his Merck team determined the structure of
.
He later served as director of the Institute of Biomedical Research at the
, where he was also Ashbel Smith Professor of
Chemistry.
In recognition for his scientific contributions, he received the
in 1960,
the
in 1967,
the
in
1986, and the
in 1990.
Legacy
[
]
The plant species
is named after Folkers.
References
[
]
^
Olson, R E (September 1, 2001).
.
Journal of Nutrition
.
131
(9):
2227–
30.
:
.
.
Shive, William (2002). "Karl August Folkers, September 1, 1906 – December 9,
1997".
Biographical Memoirs of the National Academy of Sciences
.
81
:
100–
14.
.
^
. University of Illinois Alumni Association
. Retrieved
27 June
2022
.
Narins, Brigham. (2001).
Notable Scientists From 1900 to the Present, Volume 2
. Gale Group. p. 749.
"Folkers isolated vitamin B12 in 1947, and spent the following eight years elucidating its complex- atom structure; it is used in
the treatment of pernicious anemia. He synthesized pantothenic acid in 1940, and biotin in 1945."
Acc. 90-105 - Science Service, Records, 1920s-1970s, Smithsonian Institution Archives. Accessed 29 July 2013.
Kuehl, Frederick A.; Wolf, Frank J.; Trenner, Nelson R.; Peck, Robert L.; Buhs, Rudolf P.; Howe, Eugene; Putter, Irvin;
Hunnewell, Berl D.; Ormond, Robert; Downing, George; Lyons, John E.; Newstead, E.; Chaiet, Louis; Folkers, Karl (1955). "D-4-
amino-3-isoxazolidone, a new antibiotic".
Journal of the American Chemical Society
.
77
(8):
2344–
2345.
:
.
:
.
Stammer, Charles H.; Wilson, Andrew N.; Holly, Frederick W.; Folkers, Karl (1955). "Synthesis of D-4-amino-3-isoxazolidone".
Journal of the American Chemical Society
.
77
(8):
2346–
2347.
:
.
:
.
. 26 February 2015.
.
. 31 May 2016
. Retrieved
24 March
2018
.
.
www.newyorkacs.org
.
;
(9 June 1986).
. Vol. 2. New York Botanical Garden Press. p. 4
. Retrieved
22 May
2026
.
External links
[
]
, biographical memoir by William Shive
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, President Elect (2025)
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